Recombinant CEA anticorps

N° du produit ABIN7487714

Cet anticorps Lapin Chimeric détecte spécifiquement CEA dans ISG. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant CEA anticorps (ABIN7487714)

Antigène: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CEA est non-conjugé

Application: Immunoscintigraphy (ISG)

Clone: BW431-26

Détail du produit anti-CEA anticorps

Fonction: Anti-CEA [BW431/26], Rabbit IgG, kappa

Specificité: This antibody recognizes and binds human carcinoembryonic antigen in its purified state as well as on tissue sections.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG3

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing mice with CEA positive adenocarcinoma cells preferably from lungs.

Isotype: IgG kappa

Information d'application

Indications d'application: Technetium 99-labeled (Tc-99m) BW431/26 has been used in the diagnosis and detection of colorectal carcinomas, breast cancers, bladder carcinomas, lung adenocarcinomas and their recurrences by immunoscintigraphy (PMID: 2602902, 2662074, 2685692, 2297747, 2157833, 2166552, 2383485, 1984945 ). The use of Tc-99m-BW 431/26 immunoconjugates in immunoscintigraphy resulted in reduction of radiation dose for the patient down to 5 % of the dose applied as compared with I-131 labelled MAbs (PMID: 3262953). Humanized version of this antibody also shows similar binding affinity as compared to its murine parent antibody (PMID: 1762576).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG3 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CEA

Antigène: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Autre désignation: CEA

Sujet: Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, CEACAM5, Meconium antigen 100, CD66e

UniProt: P06731